It's interesting that we only have reactions to specific games, and that certain games bother some individuals, but not others, and vice-versa. That leads me to believe that what's going on here isn't broadly a case of "motion sickness". I think individuals just have sensitivities to the unique ways that certain games render and set in motion their 3D environments.
I've been playing more of Metroid Prime, and I think what's causing me problems is the fact that there's a slight warp effect in the textures when 3D environments in the game are rotated around an axis (the player). Textures on the periphery of vision carry a slightly faster motion relative to textures at the center (focal point), and my eyes struggle to track the discrepancy. I've been able to reduce my symptoms by moving back about six feet from the screen and by taking things very slow (being careful not to make any quick or jerky movements). I'm able to play for about an hour this way before a mild headache sets in and I have to quit.
I suspect that if Metroid Prime used dual analog control, I wouldn't be having this problem.
Cybergoth, on Fri Apr 15, 2011 2:03 AM, said:
Two weeks ago I went to a neurologist with my problems and he did record an EEG of my brain, while I was sitting next to a strobe light that would constantly flash and speed up in frequency over a couple of minutes. While the EEG did not really show signs of something like an epilepsy seizure, another anomaly was found, that according to my doc does show up in ~5% of the EEGs he records. The phenomenon was, that my brains alpha waves, that normally would run at a frequency of about 15Hz, did actually sync up to the frequency of the strobe light. He said something like that my brain would go into a "photo-driven" state.
That's very interesting. Did you feel anything out of the ordinary while in this "photo-driven" state? Besides a headache, I mean.